Iatrogenic Ototoxic Hearing Loss
نویسندگان
چکیده
منابع مشابه
Ototoxic Hearing Loss and Retinoblastoma Patients
Chemotherapy is often used in the conservative management of retinoblastoma. Chemotherapy drugs, while ameliorative, can produce long-lasting side effects that potentially can affect survivor quality of life. Carboplatin is a common chemotherapy agent with known ototoxic side effects that is used in the treatment of retinoblastoma (RodriguezGalindo et al., 2003). The potential for carboplatin-i...
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Therapeutic drugs with ototoxic side effects cause significant hearing loss for thousands of patients annually. Two major classes of ototoxic drugs are cisplatin and the aminoglycoside antibiotics, both of which are toxic to mechanosensory hair cells, the receptor cells of the inner ear. A critical need exists for therapies that protect the inner ear without inhibiting the therapeutic efficacy ...
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Cyclodextrins are a family of cyclic oligosaccharides with widespread usage in medicine, industry and basic sciences owing to their ability to solubilize and stabilize guest compounds. In medicine, cyclodextrins primarily act as a complexing vehicle and consequently serve as powerful drug delivery agents. Recently, uncomplexed cyclodextrins have emerged as potent therapeutic compounds in their ...
متن کاملFactors affecting sensitivity of distortion-product otoacoustic emissions to ototoxic hearing loss.
OBJECTIVES (1) To determine the ototoxicity detection rate (sensitivity) for distortion-product otoacoustic emissions (DPOAEs) testing in adults who received ototoxic medications and experienced pure-tone threshold changes during the course of treatment; (2) to determine the extent to which DPOAE sensitivity to ototoxicity depends on the type of drug administered (platinum or antibiotic), magni...
متن کاملHEARING LOSS IN HEMODIALYSIS PATIENTS
Inner ear cells are sensitive to some metabolic and hormonal disorders, but the relation between chronic renal failure (CRF), regular dialysis treatment (RDT) and sensorineural hearing loss (SNHL) is still a debatable field. The object of this paper was to verify the presence of SNHL in patients submitted to hemodialysis with different duration due to CRF and in those submitted to conservat...
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ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1971
ISSN: 0003-4932
DOI: 10.1097/00000658-197102000-00016